So check the side-effects list to be familiar with which side-effects are associated with which drug so if you have a side-effect, youll know which drug to reduce or eliminate. To protect M10 from my COVID-19 vaccination opinions, I will no longer post about my vaccination concerns here. If you take fluvoxamine, please avoid caffeine while on the drug. Added to FLCCC protocols and Fareed-Tyson protocol among others. ICER Publishes Final Evidence Report and Policy Recommendations on Outpatient Treatments for COVID-19 - ICER. It is very safe: There is no evidence fluvoxamine is harmful and led to a worse outcome. (The fund borrows its nonprofit status from the 501(c)(3) Rockefeller Philanthropy Advisors, which managed its money until it quit, according to the Daily Beast; neither organization is related to the Rockefeller Foundation, which supports Technology Review's reporting on covid.). The NIH picks the drug that makes the most money for the drug companies regardless of long-term safety Molnupiravir! So why would we wait when lives are being lost? Steve Kirsch Nov 5, 2021 145 92 Here are the key things you should know about fluvoxamine for COVID: It works. Steve Kirsch. 22, 2021, 9:00 a.m. Steve Kirsch , a former tech entrepreneur who earned a fortune worth up to $300 million, has been showcased on TrialSite a few times for his activity supporting the clinical development of repurposed drugs for COVID-19 treatments. I've collected fluvoxamine evidence here for convenient access. (One of them, Eric Lenze, was in fact giving a presentation on fluvoxamine to the National Institutes of Health the next day.) Medium revoked my account for life. In other cases, stop cold turkey. And FrameMaker is still a niche product. The CDC has advised everyone to wear a mask. It doesnt get much better than that. With cases spiking, the Los Angeles area banned gatherings. Ivermectin has a very high quality systematic review, the highest possible level in Evidence Based Medicine. The agency quickly slapped down the comments from Kirsch, a tech mogul with a fortune once estimated at $230 million, even as the claims triggered a flurry of false social-media posts attributing. (Siliciano did not respond to requests for comment for this article.). Is fluvoxamine helpful for patients with the coronavirus? Is it - Quora The NIH wrote a bullshit rejection because the FDA told them not to approve it. My experience is very typical. This alone will give roughly a 50% effect size and explains why all of the the SSRIs are effective including those that do not activate the Sigma1 receptor (e.g., Paroxetine). I fixed the link to the fluvoxamine article. Most doctors wont use it until NIH greenlights it, no matter what the science says. So probability of successful Phase 3 can be estimated to be over 99.99% since there are tens of thousands of phase 3 studies. Less than a week later, David Seftel read about the Lenze trial, and ignored the JAMA advice. Also, this drug is only prescribed by psychiatrists so most doctors have no experience whatsoever with the drug. People who report not tolerating the drug are typically prescribed too high a dose. It never was. Early research suggests that fluvoxamine, an FDA approved medication for depression and obsessive compulsive disorder, can be an effective early treatment for COVID-19. Steve is a Silicon Valley entrepreneur and philanthropist who founded the COVID-19 Early Treatment Fund (CETF) at the beginning of the pandemic. Think about it Molnupiravir has a 50% risk reduction whereas fluvxoamine is over 90%. See the repository above. NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). David Boulware, a researcher at the University of Minnesota, received $125,000 to test the drug against covid. Nov 12: Steve Kirsch gives talk on CETF to HarvardBusiness School hosted by Dr. Seftel Nov 13:Mass COVID outbreak at GGF is now publiclyknown Nov 16: Seftel, the track physician at GGF, startsFLV . But Kirsch is also motivated by an unsatisfied competitive streak. Jeffrey Glenn, an infectious disease professor at Stanford University, calls the inaction on the current evidence on the table "criminal.". 47).. Or just depression about the vaccine mandates? Think about it Molnupiravir has a 50% risk reduction whereas fluvxoamine is over 90%. My publicly shared concerns regarding the safety of the COVID-19 vaccines may have had a negative impact on my company, M10. Steve Kirsch - Wikipedia just like ivermectin). Article about the rejection (Stat News) Article about the fluvoxamine rejection (The Verge) NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). If the drug is started right after symptoms, weve seen 100% prevention in hospitalization. Decreasing the dosage or stopping the medication will mitigate symptoms within hours. For example, tylenol+caffeine+fluvoxamine can lead to serotonin syndrome. After publication of the recommendation in December 2021, the NIH did absolutely nothing change their recommendation. This was shown to be very tolerable (no side effects in 99% of patients) and extremely effective (no hospitalizations and death if you start it ASAP after first symptoms). How covid-19 conspiracy videos keep getting millions of views. He prefers iconoclastic approaches, whether by directly funding asteroid detection or advocating for nuclear power to combat global warming. But they dont want their names used. Skirsch.io Steve Kirsch Home page Fluvoxamine, COVID, pandemic, . In November, CETF gave the group an additional $500,000 for a phase 3 clinical trial that might show conclusive proof of efficacy. Fluvoxamine was reportedly added to just 2 practice guidelines (Ontario and Johns Hopkins). Note that some of these articles are inaccurate. On his blog, Covid-19 Data Science, he has extensivelyand mercilesslyunpacked Kirschs evidence for the vaccine death claims. . The anecdotal data of 100% success rates is further icing on the cake. While YouTube has repeatedly taken down the full video of the DarkHorse episode, various clips have been watched over 4 million times, and the full audio remains available on Spotify. By Steve Kirsch Mar 14, 2021 Fluvoxamine, Proxalutamide, and Ivermectin: 100% success I'm very bullish on two drug combos since it is rare for a single drug to be 100% successful. Now weve lost the high ground, Morris told me. In 2016, it was the 135th most-prescribed medication in the United States, with more than 4 million prescriptions. Doctors who have used fluvoxamine in the US and other countries swear by it. Mouse Systems is not a household word, he told the journalist. Kirsch, though, often relies on the heartstrings to smooth over a lack of data. Also, for people who cant tolerate fluvoxamine for whatever reason (nausea, jittery, etc), this is the alternative. A very short op-ed arguing for using fluvoxamine against COVID. When I asked him why so many experts in the field disagreed with him, he alleged there were effortseither malicious or negligentto suppress evidence of cheap, effective covid treatments. We don't know why the NIH panel is ignoring fluvoxamine and we aren't allowed to find out. Jan 17. The US government accused Janssen of improperly promoting the antipsychotic drug Risperdal to dementia patients despite the drug increasing deaths in the elderly. His efforts became more focused on medical research when, in 2007, he was diagnosed with a rare blood cancer. I have all of these on hand and I load up on vitamin D3 every day. See this Wall Street Journal op-ed. (The ivermectin data are trash, Feinberg told me. Unfortunately, as Jeffrey Morris at UPenn points out, public health officials and scientists have done plenty to undermine their own authority, like claiming masks dont work, downplaying the natural immunity conveyed by previous covid infections, and not doing enough public communication about vaccine safety surveillance systems. But thats not a surprise, according to researchers who conducted them: the vast majority of trials for any drug end in failure. Stopping the meds will return you to your normal self. Dr. Seftel's paper has been accepted for publication and will appear in OFID in early February. Ms Tech | Pexels (hands); Kirsch (skirsch.com), Ivermectin has been falsely promoted as a covid treatmentbut for those who use the drug legitimately, seeing it become a piece of anti-vaccine misinformation is disconcerting, supports Technology Review's reporting on covid, anti-covid-vaccine, pro-ivermectin pundit, Roomba testers feel misled after intimate images ended up on Facebook, How Rust went from a side project to the worlds most-loved programming language. Why the FDA should grant an EUA for fluvoxamine immediately, Links to evidence about fluvoxamine including the public data repository, Here's the first one: It is perhaps the greatest unnecessary loss of life in American history. Hes also made several videos and podcasts with Vladimir Zelenko, the conspiracy theorist doctor who convinced Trump to take hydroxychloroquine. The data we have today with just 2 clinical trials (RCT and confirmatory RWE) is compelling. For example, tylenol+caffeine+fluvoxamine can lead to serotonin syndrome. To date, the #1 drug with the most evidence to make a significant difference, without any doubt, is fluvoxamine. This 1/6 of the dose the FDA has approved for OCD (the labelled indication for fluvoxamine)! There are reports of people who cant tolerate the drug, but they stop using it and nothing bad happened. Fauci wants the vaccine to be the only option, Cliff Lane works for Fauci, and Cliff follows his orders. Hes adept at debate, rapidly shifting the premise of a conversation to put the other person on the back foot. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. . In September, Kirsch emailed Morris asking him to estimate the maximum number of deaths caused by vaccines. We didnt come up with better mouse technology than Microsoft did. Note that a total of 77 people got the drug, not 65. Online. Should I take ivermectin or fluvoxamine or both? - Quora Fluvoxamine (Luvox) is a Selective Serotonin Receptor Inhibitor (SSRI) that is clinically indicated for OCD in children, and can be used off label for depression. . Fluvoxamine is a very safe drug on market for 37 years, tens of millions of people have taken it, no record in scientific literature of anyone dying on overdose, and according to doctors that know the drug the best, about as dangerous as taking a Tylenol. That study was featured on 60 Minutes. 9th International Congress on Psychopharmacology 5th International Symposium on Child and Adolescent Psychopharmacology Medicine today isnt about saving your life. Thats what creates some of these heroes.. In May, all 12 members of CETFs scientific advisory board resigned, citing his alarming dangerous claims and erratic behavior. Dosage there is 30mg once a day. Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. In the early days of the pandemic, as billions of dollars poured into the hunt for novel treatments and vaccines, veteran Silicon Valley entrepreneur Steve Kirsch did what hes always done: He went looking for an underdog. Be warned!. This looks ominous, but it harmless. FDA official fluvoxamine rejection. The most stunning study of fluvoxamine ever done was at the Golden Gate Fields racetrack in November 2020, right after the WashU trial was published in JAMA. Thanks for working tirelessly to help others. In short, a lot of mumbo jumbo. We need to keep people out of the hospital in the first place. Flavio Cadegiani and Steve Kirsch's studies didn't make the cut. Fluvoxamine, Proxalutamide, and Ivermectin: 100% success MD, MPH; Steven C. Marcus, PhD. Incriminating evidence - Steve Kirsch's newsletter - Substack It has shown to be 100% protective of hospitalization in 2 clinical trials. Design thinking was supposed to fix the world. Timing is everything with respect to outcomes. Doctors have no excuse for not prescribing. Silence from the medical community. Please. I asked to give a talk about COVID at MIT, but they couldn't find a faculty member to sponsor it. To scientists, giving fluvoxamine a chance means running a large trialnot giving it to individual patients in the clinic, off-label and outside the context of active data collection and analysis. So much for evidence-based medicine. The U of M's study focused on three common drugs: ivermectin, metformin, and fluvoxamine. As of January 18, 2021, the CDC estimates that 90,000 Americans will die from COVID in just the next 3 weeks. reach out to us at Part of TV News Archive. fluvoxamine - Steve Kirsch Home page Keyword: mit Worst case, if we ignore all additional evidence so the average is a 60% pass rate. Ive used it personally at 50mg twice a day and experience no adverse events at all. The Wall Street Journal thinks it should be used (and that the NIH is wrong for waiting for more clinical trials). Decreasing the dosage or stopping the medication will mitigate symptoms within hours. He has been a medical philanthropist for more than 20 years. He says that Facebook took down one of his posts announcing his appearance on 60 Minutes. Independent appraisal committee votes 11-2 that the evidence is not adequate to demonstrate a net health benefit for molnupiravir over symptomatic care alone; Paxlovid and fluvoxamine receive more favorable votes. Boulware disputes that, and says that although Kirschs funding was important, his statements about drugs and vaccines have proven problematic. In a recent post, discussing claims Kirsch made during a three-minute comment at an FDA public forum, Morris wrote: In spite of many pages of writing and claims of over a dozen independent analyses verifying their results, their evidence falls far short of substantiating these dramatic conclusions, including a claim that vaccines have caused >250K excess deaths in the USA.. By Steve Kirsch in fluvoxamine Feb 14, 2021 The case for fluvoxamine for treating COVID-19 A very short op-ed arguing for using fluvoxamine against COVID. Can I see your risk-benefit analysis?. The race to find covid-19 drug treatments that actually work, The antimalarial drug Trump took for covid might actually be dangerous. The NIH did nothing despite the fact the that NIH, FDA, CDC, and academic institutions participated in the panel, this is NOT about the science. But the confusion provided a fertile breeding ground for skeptics. It is an amazing drug and is a very simple safe way to avoid long-haul COVID symptoms. Don't underestimate the virus. Fluoxetine is just as effective. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. Other SSRIs work as well, but fluvoxamine activates the Sigma-1 receptor the most of the SSRIs which is why it was chosen. Sage Hana. We dont want to feed the anti-vaccine trolls, so we actively suppress clear scientific data. Los Altos Hills resident touts fluvoxamine as COVID-19 treatment and here are the slides I used in, Collections of op-eds and presentations about fluvoxamine, Please see my answer on Quora (Clayton Fox, Marty Makary, and Jeffrey Klausner). How I recommend people treat COVID and the fascinating backstory of how fluvoxamine was discovered. And, according to three members of CETFs scientific advisory board, he put pressure on them to promote fluvoxamine for clinical use without conclusive data that it worked for covid. upcoming events, and more. These people never called the researchers whose trials they claimed showed no effect. Vitamin D, NAC, betadine, aspirin, and Nigella sativa are all super cheap, effective, and available without a prescription. It works best when it is given early, as soon as symptoms start. Summary of key evidence. Antidepressant fluvoxamine could keep mild COVID-19 from worsening So much for evidence-based medicine. Fluvoxamine - The backstory T he i nsi de st ory behi nd how f l uvoxami ne became a CO V I D t herapy By Steve Kirsch Last updated: June 3, 2021 . But fear of trying something new prevents any doctor from giving this drug a try. Tech millionaire Steve Kirsch went from covid trial funder to While Fauci was crafting national pandemic policies, Fauci's wife [Christine Grady, Chief Bioethicist, NIH] was back stopping [them]." Report coming soon. On January 22, 2021, thirty key opinion leaders (KOL) from NIH, CDC, and leading academic institutions met to review the evidence for using fluvoxamine for treating COVID. I fully expected both organizations to do absolutely nothing. Sadly, doctors and public health officials refuse to instruct patients to seek early treatment. Thats why they didnt change their recommendation when the Phase 3 trial was published in Lancet. Kirsch did a lot of things right when he set up CETF. He's discovered a common medication that's highly effective in minimizing the impacts of COVID-19 - two studies have proven so. ALWAYS check with your doctor and report any medications you are taking before or plan to take after you start taking fluvoxamine. This post was written to memorialize the corruption. Here are the key things you should know about fluvoxamine for COVID: It works. Summarizes the 5 observational studies, RCT, RWE, and some of the more interesting anecdotal data. 533. Most recent articles first. Who knows, Morris replied. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. . And he wont talk to you either if you ask nosy questions like Cliff, my risk benefit analysis shows you should be rushing to recommend this drug. iRobot said it had consent to collect this kind of data from inside homesbut participants say otherwise. Proven in clinical use all over the world. [https://www.quora.com/What-is-the-current-treatment-for-Covid-19/answer/, The most urgent need in the country right now is to reduce. committee votes 11-2 that the evidence is not adequate to demonstrate a net health benefit for molnupiravir over symptomatic care alone; Paxlovid and fluvoxamine receive more favorable votes, This site requires JavaScript to run correctly. By Steve Kirsch Last updated: March 14, 2021 After I appeared on the60 Mi nut es story about fluvoxamine,I've received a lot of questions from people about how to treat COVID.